- Sodium perchlorate
- Potassium iodide
Levothyroxine is used to treat hypothyroidism. It acts like the thyroid hormone T4, which is produced naturally in the body. It influences cell development and growth, increases energy metabolism, regulates body temperature, and accelerates metabolism.
Liothyronine serves to bridge the hypothyroid phases prior to radioiodine therapy in cases of thyroid carcinoma. T3 alone is not suitable for long-term therapy.
Thiamazole belongs to the group of thyrostatic drugs and is used to treat hyperthyroidism. Depending on the dose used, it inhibits the synthesis of thyroid hormones in the thyroid gland during blocking of thyroid gland peroxidase.
Propylthiouracil (PTU), like Thiamazole, causes dose-dependent inhibition of the thyroid hormones with the blocking of thyroid peroxidase. In addition, PTU inhibits the conversion that takes place in the body of the prohormone thyroxin into the active form of the thyroid hormone triiodothyronine (T3).
Sodium Perchlorate (Irenat) blocks the uptake of inorganic iodine by the thyroid gland and in that way decelerates hyperfunction of that organ.
Potassium iodide in tablet form protects the thyroid gland in the event of nuclear disasters. When there is an atomic reactor accident, radioactive iodine can be released and subsequently ingested in food or inhaled. Potassium iodide tablets prevent the uptake of radioactive iodine by the thyroid gland. Due to the high amount of iodine, the thyroid gland is suppressed for several days and disabled (Wolff-Chaikoff effect). In this way, radioactive iodine is quickly excreted and thyroid cancer can be avoided.